Drug for Refractory Psoriatic Arthritis Shows Promise in Clinical Trial

In a pivotal phase-3 clinical trial led by a Stanford University School of Medicine investigator, patients with psoriatic arthritis for whom standard-of-care pharmaceutical treatments have provided no lasting relief experienced a significant reduction in symptoms, including joint tenderness and swelling, when they were given a new drug. The 24-week randomised, double-blind, placebo-controlled trial was conducted [...]

By |2017-05-31T11:56:15+01:00May 31st, 2017|Rheumatology|0 Comments

Benefits of Learning Sessions for Managing Rheumatoid Arthritis

A new study found that group-based quality improvement sessions help rheumatologists care for rheumatoid arthritis patients with the recommended ‘treat to target’ approach to care. This approach involves setting a target for treatment, measuring progress towards achieving the target regularly, altering treatments until reaching and maintaining target, and sharing the decisions with patients. The randomised [...]

By |2017-05-31T12:04:39+01:00May 31st, 2017|Rheumatology|0 Comments

Key Stem Cells for Repairing Knee Joints Identified

Stem cells that seem key for maintaining and repairing the body’s knee joints have been identified by scientists. Researchers from the University of Aberdeen’s Centre for Arthritis and Musculoskeletal Health recently published the findings in Nature Communications. Injury or conditions, such as arthritis, cause the normally thin membrane to become inflamed and thicken, creating more [...]

By |2017-05-31T12:03:15+01:00May 31st, 2017|Rheumatology|0 Comments

New Lung ‘Organoids’ in a Dish Mimic Features of Full-Size Lung

New lung ‘organoids’ – tiny 3D structures that mimic features of a full-sized lung – have been created from human pluripotent stem cells by researchers at Columbia University Medical Centre (CUMC). The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding [...]

By |2017-05-30T10:47:34+01:00May 30th, 2017|Respiratory|0 Comments

Prototype Drug Uses Novel Mechanism to Treat Lung Cancers

Lung cancer tumours were prevented in mice by a novel small molecule that directly activates a tumour suppressor protein. 45 researchers, including eight students from the Young Scientist Foundation and Mark R Chance, PhD, Vice Dean for Research at Case Western Reserve School of Medicine, collaborated to screen a series of drug-like molecules for their ability [...]

By |2017-05-30T10:33:56+01:00May 30th, 2017|Respiratory|0 Comments

Drug Shows Promise for Tackling Drug Scarring

People with a lung scarring condition that leaves them fighting for breath could be helped by a new medication, research suggests. Results from an early stage clinical trial show that the new drug has no serious side-effects and was well-tolerated by patients with the condition, called Idiopathic Pulmonary Fibrosis (IPF). The findings also reveal promising [...]

By |2017-05-30T10:17:03+01:00May 30th, 2017|Respiratory|0 Comments

Study Unravels the Genetics of Childhood ‘Overgrowth’

Researchers have undertaken the world’s largest genetic study of childhood overgrowth syndromes – providing new insights into their causes, and new recommendations for genetic testing. Overgrowth syndromes describe conditions that cause children to be taller and to have a bigger head size than expected for their age, and also to have an intellectual disability or [...]

By |2017-05-26T12:24:39+01:00May 26th, 2017|Oncology|0 Comments

Prescription History to Aid Earlier Cancer Diagnosis

Looking for patterns in prescriptions and other data could help guide GP referrals, especially in patients with non-specific symptoms that don’t obviously indicate cancer. Only about half of those with the most common cancers have ‘red-flag’ symptoms. And this is even lower in cancers with poor survival rates such as pancreatic, stomach, ovarian and brain [...]

By |2017-05-26T12:16:59+01:00May 26th, 2017|Oncology|0 Comments

Technology Helps Preserve Fertility of Boys with Cancer

Washington State University (WSU) researchers have found a promising way to preserve sperm stem cells so boys could undergo cancer treatment without risking their fertility. Adult men can have their sperm frozen before undergoing radiation or chemotherapy, both of which can render sperm infertile. But boys who haven’t been through puberty can only have sperm [...]

By |2017-05-26T12:08:54+01:00May 26th, 2017|Oncology|0 Comments

Predatory Bacteria Kills Multi-Drug Resistant Bacteria on Eyes

Scientists have developed a new method to clear antibiotic resistant bacteria from the surface of the eye — introducing a new strain of bacteria that preys on other microorganisms. The research was recently presented at the 2017 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) in Baltimore, Md. Experiments on rabbit eyes [...]

By |2017-05-25T10:59:17+01:00May 25th, 2017|Ophthalmology|0 Comments